The point at which even I stop playing: crashes of no continue.
When I originally tried playing Deadly Premonition, I stopped because it was impossible to get out of the hospital without crashing.
Revisiting the game with the current brew of fixes posted in Steam Guides, I found that less of a pickle. So much as it seems the game fires off an exit after x time, almost as if it keeps leaking resources or something. Faster while driving and mapping than wondering around the shadow world.
And then, I save at the community center, go walk the dog, come back, and find the game silently crashes to desktop the moment it is done loading my save file :'(.
This reminds me that the '360 version is like $15 in the used game bin. I'd like to hope the backwards compatibility and old release, suck less than the PC port that was pushed to Steam and GOG.